Rayburn may refer to:
- People
- Gene Rayburn (1917–1999), U.S. host of TV's Match Game
- Sam Rayburn (1881–1961), U.S. Speaker of the House
- Places
- Rayburn House Office Building, a Congressional building
- Rayburn Range, a stove
- Rayburn Township, Pennsylvania
- Other
- Rayburn (band), a 1970s rock band from Little Rock, Arkansas