Gene Expression
Two isoforms are produced from the same RORC gene, probably by selection of alternative promoters.
- RORγ (also referred to as RORγ1) – produced from an mRNA containing exons 1 to 11.
- RORγt (also known as RORγ2) – produced from an mRNA identical to that of RORγ, except that the two 5'-most exons are replaced by an alternative exon, located downstream in the gene. This causes a different, shorter N-terminus.
Read more about this topic: RAR-related Orphan Receptor Gamma
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