Types of Rab Proteins
There are approximately 70 different Rabs that have been identified in humans thus far. They are mostly involved in vesicle trafficking. Their complexity can be understood if thought of as address labels for vesicle trafficking, defining the identity and routing of vesicles.
| Name | Subcellular location |
|---|---|
| RAB1 (YPT1) | ER, golgi complex |
| RAB2 | ER, cis-golgi network |
| RAB3A | secretory and synaptic vesicles |
| RAB4 | early endosomes |
| RAB5A | clathrin-coated vesicles, plasma membranes |
| RAB5C | early endosomes |
| RAB6 | medial- and trans-golgi network |
| RAB7 | late endosomes |
| RAB8 | basolateral secretory vesicles |
| RAB9 | late endosome, trans-golgi network |
| RAB11 | recycling endosomes |
| RAB18 | lipid droplets, golgi, endoplasmic reticulum |
| RAB39a | binds Caspase-1 in inflammasome |
| SEC4 | secretory vesicles |
Read more about this topic: Rab (G-protein)
Famous quotes containing the words types of, types and/or proteins:
“Our children evaluate themselves based on the opinions we have of them. When we use harsh words, biting comments, and a sarcastic tone of voice, we plant the seeds of self-doubt in their developing minds.... Children who receive a steady diet of these types of messages end up feeling powerless, inadequate, and unimportant. They start to believe that they are bad, and that they can never do enough.”
—Stephanie Martson (20th century)
“The rank and file have let their servants become their masters and dictators.... Provision should be made in all union constitutions for the recall of leaders. Big salaries should not be paid. Career hunters should be driven out, as well as leaders who use labor for political ends. These types are menaces to the advancement of labor.”
—Mother Jones (1830–1930)
“Civilization means food and literature all round. Beefsteaks and fiction magazines for all. First-class proteins for the body, fourth-class love-stories for the spirit.”
—Aldous Huxley (1894–1963)