Quadruple may refer to:

  • 4-Tuple, a mathematical structure consisting of a sequence of four elements
  • Quadruple, a term for winning four association trophies
  • Quad (figure skating), a figure skating jump
  • Home run in baseball
  • Quadruple-precision floating-point format in computing
  • Quadruple Alliance (disambiguation), the name of a number of military alliances
  • A multiple birth with four offspring