Protein Structure - Computational Prediction of Protein Structure

Computational Prediction of Protein Structure

The generation of a protein sequence is much easier than the determination of a protein structure. However, the structure of a protein gives much more insight in the function of the protein than its sequence. Therefore, a number of methods for the computational prediction of protein structure from its sequence have been developed. Ab initio prediction methods use just the sequence of the protein. Threading and Homology Modeling methods can build a 3D model for a protein of unknown structure from experimental structures of evolutionary related proteins.

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