A primary transcript is an RNA molecule that has not yet undergone any modification after its synthesis such as methylation, or the addition of a Poly-A tail. For example, a precursor messenger RNA (pre-mRNA) is a primary transcript that becomes a messenger RNA (mRNA) after processing, and a primary microRNA (pri-miRNA) precursor becomes a microRNA (miRNA) after processing.
Famous quotes containing the word primary:
“Parental attitudes have greater correlation with pupil achievement than material home circumstances or variations in school and classroom organization, instructional materials, and particular teaching practices.”
—Children and Their Primary Schools, vol. 1, ch. 3, Central Advisory Council for Education, London (1967)