Primary Progressive Aphasia - Classification

Classification

The classification of Primary Progressive Aphasias, has a clinical and pathological overlap of Frontotemporal Lobar Degeneration (FTLD) spectrum of disorders and Alzheimer pathology. In the classical Mesulam criteria for primary progressive aphasia there are 2 variants: a non-fluent type Progressive Nonfluent Aphasia (PNFA) and a fluent type Semantic Dementia (SD). The third variant of primary progressive aphasia Logopenic Progressive Aphasia (LPA) is an atypical form of Alzheimer's. And these are the three classifications of primary progressive aphasia.