PRI may refer to:
- Pacific Research Institute, a California-based free market think tank
- Paleontological Research Institution, Ithaca, New York
- Panchayati Raj Institutions
- Partito Repubblicano Italiano, the Italian Republican Party, est. 1895
- Partido Revolucionario Institucional (PRI), the Institutional Revolutionary Party in Mexico since 1929
- Penal Reform International, a non-governmental organization
- Perceptual Reasoning Index, one of the four major components of intelligence in the WAIS-IV test
- Perth Royal Infirmary, a hospital in Perth, Scotland
- Photochemical reflectance Index
- Political risk insurance
- Pollution reduction and investment, revised name for "cap and trade" (otherwise known as emissions trading)
- Population Research Institute, a pro-life nonprofit in Virginia
- IATA airport code for Praslin Island Airport, in the Seychelles
- Primary Rate Interface, telecommunication standard
- Primate Research Institute
- Principles for Responsible Investment (PRI)
- Public Radio International, a Minneapolis-based American public radio organization
- The ISO 3166-1 3-letter country code and an abbreviation for Puerto Rico
- Puerto Rico Islanders