The pretectal area, or pretectum, is a midbrain structure composed of seven nuclei and comprises part of the subcortical visual system. Through reciprocal bilateral projections to the retina, it is primarily involved in mediating behavioral responses to acute changes in ambient light such as the pupillary light reflex, the optokinetic reflex, the accommodation reflex, and temporary changes to the circadian rhythm. In addition to the pretectum's role in the visual system, the anterior pretectal nucleus has been found to mediate somatosensory and nociceptive information.
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