Bipolar Depression
In a single controlled study of twenty one patients, pramipexole was found to be highly effective in the treatment of bipolar depression. Treatment was initiated at 0.125mg t.i.d. and increased at a rate of 0.125mg t.i.d. to a limit of 4.5mg qd until the patients' condition satisfactorily responded to the medication or they could not abide the side effects. The final average dosage was 1.7mg ± .90mg qd. The incidence of hypomania in the treatment group was no greater than in the control group.
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Famous quotes containing the word depression:
“Geez, if I could get through to you, kiddo, that depression is not sobbing and crying and giving vent, it is plain and simple reduction of feeling. Reduction, see? Of all feeling. People who keep stiff upper lips find that it’s damn hard to smile.”
—Judith Guest (b. 1936)