Muscarinic Potassium Channel
See also G protein-coupled inwardly-rectifying potassium channel
Some types of potassium channels are activated by muscarinic receptors and these are called muscarinic potassium channels (IKACh). These channels are a heterotetramer composed of two GIRK1 and two GIRK4 subunits. Examples are potassium channels in the heart, which, when activated by parasympathetic signals through M2 muscarinic receptors, cause an outward current of potassium, which slows down the heart rate.
Read more about this topic: Potassium Channel
Famous quotes containing the word channel:
“This is what the Church is said to want, not party men, but sensible, temperate, sober, well-judging persons, to guide it through the channel of no-meaning, between the Scylla and Charybdis of Aye and No.”
—Cardinal John Henry Newman (18011890)