Potassium-sparing Diuretic - Chemical Structure

Chemical Structure

Potassium-sparing diuretics do not share any obvious chemical similarities, except for the steroid-structure of the aldosterone antagonists. Those in clinical use include:

  • Epithelial sodium channel blockers
    • Amiloride
    • Triamterene
  • Aldosterone antagonists:
    • Spironolactone
    • Eplerenone

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