Related Animal Research
- Recently, two publications have reported the renewal of ovarian follicles from germline stem cells. Prior to these papers it was believed that the number of oocytes was fixed.
- While the primary cause of the end to menstrual cycles is the exhaustion of ovarian follicles, there is some evidence that a defect in the hypothalamus is critical in the transition from regular to irregular cycles. This is supported by at least one study in which transplantation of ovaries from old rats to young ovariectomized rats resulted in follicular development and ovulation. Also, electrical stimulation of the hypothalamus is capable of restoring reproductive function in aged animals. Due to the complex interrelationship among the hypothalamus, pituitary and ovaries (HPO axis) defects in the functioning of one level can cause defects on the other levels.
Read more about this topic: Poor Ovarian Reserve
Famous quotes containing the words related, animal and/or research:
“A parent who from his own childhood experience is convinced of the value of fairy tales will have no difficulty in answering his child’s questions; but an adult who thinks these tales are only a bunch of lies had better not try telling them; he won’t be able to related them in a way which would enrich the child’s life.”
—Bruno Bettelheim (20th century)
“Nobody can misunderstand a boy like his own mother.... Mothers at present can bring children into the world, but this performance is apt to mark the end of their capacities. They can’t even attend to the elementary animal requirements of their offspring. It is quite surprising how many children survive in spite of their mothers.”
—Norman Douglas (1868–1952)
“The working woman may be quick to see any problems with children as her fault because she isn’t as available to them. However, the fact that she is employed is rarely central to the conflict. And overall, studies show, being employed doesn’t have negative effects on children; carefully done research consistently makes this clear.”
—Grace Baruch (20th century)