Related Animal Research
- Recently, two publications have reported the renewal of ovarian follicles from germline stem cells. Prior to these papers it was believed that the number of oocytes was fixed.
- While the primary cause of the end to menstrual cycles is the exhaustion of ovarian follicles, there is some evidence that a defect in the hypothalamus is critical in the transition from regular to irregular cycles. This is supported by at least one study in which transplantation of ovaries from old rats to young ovariectomized rats resulted in follicular development and ovulation. Also, electrical stimulation of the hypothalamus is capable of restoring reproductive function in aged animals. Due to the complex interrelationship among the hypothalamus, pituitary and ovaries (HPO axis) defects in the functioning of one level can cause defects on the other levels.
Read more about this topic: Poor Ovarian Reserve
Famous quotes containing the words related, animal and/or research:
“The question of place and climate is most closely related to the question of nutrition. Nobody is free to live everywhere; and whoever has to solve great problems that challenge all his strength actually has a very restricted choice in this matter. The influence of climate on our metabolism, its retardation, its acceleration, goes so far that a mistaken choice of place and climate can not only estrange a man from his task but can actually keep it from him: he never gets to see it.”
—Friedrich Nietzsche (1844–1900)
“All things are flowing, even those that seem immovable. The adamant is always passing into smoke. The plants imbibe the materials which they want from the air and the ground. They burn, that is, exhale and decompose their own bodies into the air and earth again. The animal burns, or undergoes the like perpetual consumption. The earth burns, the mountains burn and decompose, slower, but incessantly.”
—Ralph Waldo Emerson (1803–1882)
“... research is never completed ... Around the corner lurks another possibility of interview, another book to read, a courthouse to explore, a document to verify.”
—Catherine Drinker Bowen (1897–1973)