Polyclonal B Cell Response - Humoral Response To Infection

Humoral Response To Infection

For more details on this topic, see Immune system.

Diseases which can be transmitted from one organism to another are known as infectious diseases, and the causative biological agent involved is known as a pathogen. The process by which the pathogen is introduced into the body is known as inoculation, and the organism it affects is known as a biological host. When the pathogen establishes itself in a step known as colonization, it can result in an infection, consequently harming the host directly or through the harmful substances called toxins it can produce. This results in the various symptoms and signs characteristic of an infectious disease like pneumonia or diphtheria.

Countering the various infectious diseases is very important for the survival of the susceptible organism, in particular, and the species, in general. This is achieved by the host by eliminating the pathogen and its toxins or rendering them nonfunctional. The collection of various cells, tissues and organs that specializes in protecting the body against infections is known as the immune system. The immune system accomplishes this through direct contact of certain white blood cells with the invading pathogen involving an arm of the immune system known as the cell-mediated immunity, or by producing substances that move to sites distant from where they are produced, "seek" the disease-causing cells and toxins by specifically binding with them, and neutralize them in the process–known as the humoral arm of the immune system. Such substances are known as soluble antibodies and perform important functions in countering infections.

• Types of White blood cells (WBCs)

• Neutrophil

• Eosinophil

• Basophil

• Lymphocyte

• Monocyte

• Macrophage