Ploidy - Haploidisation

Haploidisation (haploidization) is the process of creating a haploid cell (usually from a diploid cell).

A laboratory procedure called haploidisation forces a normal cell to expel half of its chromosomal complement. In mammals this renders this cell chromosomally equal to sperm or egg. This was one of the procedures used by Japanese researchers to produce Kaguya, a fatherless mouse.

Haploidisation sometimes occurs in plants when meiotically reduced cells (usually egg cells) develop by parthenogenesis.

A rare genetic disorder that has occurred in a total of 7 recorded cases is Detrimental Haploidy Syndrome where the somatic cells of the human body are haploid after the first division of cells from fertilisation. As a result of this a human with this syndrome is unfortunately prone to other diseases and unable to reproduce.

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