Platelet-activating Factor - Evolution

Evolution

The production of PAF can be found in the fossil records of protozoan’s, yeasts, plants, bacteria, and mammals. The oldest example of PAF being used in a regulatory role was found in protozoans. The regulatory role is thought to diverge from that point and be maintained as living organisms started to evolve. During evolution, functions of PAF in the cell have been changing and enlarging.

PAF has been found in plants but its function has not yet been determined.

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