Clinical Features
The prepatent period in the human ranges from 12 to 20 days. Some forms in the liver have delayed development and relapse may occur after periods of up to 4 years after infection.
The developmental cycle in the blood lasts approximately 49 h. An examination of records from induced infections indicated that there were an average of 10.3 fever episodes of > or = 101 degrees F and 4.5 fever episodes of > or = 104 degrees F. Mean maximum parasite levels were 6,944/microl for sporozoite-induced infections and 7,310/microl for trophozoite-induced infections.
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