Surface Antigens
Terminally differentiated plasma cells express relatively few surface antigens, and do not express common pan-B cell markers, such as CD19 and CD20. Instead, plasma cells are identified through flow cytometry by their additional expression of CD38, CD78, the Interleukin-6 receptor and lack of expression of CD45. In humans, CD27 is a good marker for plasma cells, naive B cells are CD27-, memory B-cells are CD27+ and plasma cells are CD27++.
CD38 and CD138 are expressed at high levels.
Read more about this topic: Plasma Cell
Famous quotes containing the word surface:
“And yet we constantly reclaim some part of that primal spontaneity through the youngest among us, not only through their sorrow and anger but simply through everyday discoveries, life unwrapped. To see a child touch the piano keys for the first time, to watch a small body slice through the surface of the water in a clean dive, is to experience the shock, not of the new, but of the familiar revisited as though it were strange and wonderful.”
—Anna Quindlen (b. 1952)