Pipestone may refer to:
- Catlinite, a type of red, carvable rock that was used by Native Americans for pipes and effigies
- Places in Canada
- Pipestone, Manitoba
- Pipestone No. 92, Saskatchewan, Canada, a former name of the Rural Municipality of Walpole No. 92
- Pipestone Creek, in central Alberta, Canada
- Pipestone Pass (Alberta), a pass in Banff National Park, Alberta (see List of passes of the Rocky Mountains)
- Pipestone River (disambiguation), any of several rivers in Canada
- Places in the United States
- Pipestone Township, Michigan
- Pipestone, Minnesota
- Pipestone County, Minnesota
- Pipestone Pass (Montana), a pass on the Continental Divide of the Americas in Montana
- Pipestone Region, in southwest Minnesota
- Pipestone National Monument, located near Pipestone, Minnesota
- Other
- Pipestone Area High School, the public high school in Pipestone, Minnesota
- Pipestone Area School District, the public school district serving the community of Pipestone
- Pipestone Golf Course, in Miamisburg, Ohio, USA