Medical Research
Indian gooseberry has undergone preliminary research, demonstrating in vitro antiviral and antimicrobial properties. There is preliminary evidence in vitro that its extracts induce apoptosis and modify gene expression in osteoclasts involved in rheumatoid arthritis and osteoporosis. It may prove to have potential activity against some cancers. One recent animal study found treatment with E. officinalis reduced severity of acute pancreatitis (induced by L-arginine in rats). It also promoted the spontaneous repair and regeneration process of the pancreas occurring after an acute attack.
Experimental preparations of leaves, bark or fruit have shown potential efficacy against laboratory models of disease, such as for inflammation, cancer, age-related renal disease, and diabetes.
A human pilot study demonstrated a reduction of blood cholesterol levels in both normal and hypercholesterolemic men with treatment. Another recent study with alloxan-induced diabetic rats given an aqueous amla fruit extract has shown significant decrease of the blood glucose, as well as triglyceridemic levels and an improvement of the liver function caused by a normalization of the liver-specific enzyme alanine transaminase activity.
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