Personal Genomics - Projects and Services Already Available

Projects and Services Already Available

• The Genographic Project is a project of the National Geographic Society and IBM to collect DNA samples to map historical human migration patterns. Launched in 2005, with 500,000 public participants as of December 2012, it helped to create the direct-to-consumer (DTC) genetic testing industry.
• The Personal Genome Project (PGP) is a long term, large cohort study based at Harvard Medical School which aims to sequence and publicize the complete genomes and medical records of 100,000 volunteers, in order to enable research into personal genomics and personalized medicine.
• SNPedia is a wiki that collects and shares information about the consequences of DNA variations, and through the associated program Promethease, anyone who has obtained DNA data about themselves (from any company) can get a free, independent report containing risk assessments and related information.
• deCODEme.com charged $1100 to carry out genotyping of approximately 1 million SNPs and provided risk estimates for 47 diseases as well as ancestry analyses. However, sales of genetic scans direct to consumer through deCODEme have now been discontinued.
• Existence Genetics provides genetic testing services through healthcare providers and health and wellness organizations, with prices starting at $299. This company provides testing for over 1,200 common and rare diseases and traits, including heart disease, cancer, autoimmune diseases, obesity, nutrigenomics, pharmacogenomics, fitness & athletic performance, preventable sudden cardiac death, and malignant hyperthermia. Existence Genetics provides fitness & athletic performance genetic testing services for Equinox Fitness.
• Navigenics, began offering SNP-based genomic risk assessments as of April 2008. Navigenics is medically focused and emphasizes a clinician's and genetic counselor's role in interpreting results. Affymetrix Genome-Wide Human SNP Array 6.0, which genotypes 900,000 SNPs.
• Pathway Genomics analyzes over 100 genetic markers to identify genetic risk for common health conditions such as melanoma, prostate cancer and rheumatoid arthritis.
• 23andMe sells mail order kits for SNP genotyping. The information is stored in a user profile and used to estimate the genetic risk of the consumer for 178 diseases and conditions, as well as ancestry analysis. 23andMe utilizes a DNA array manufactured by Illumina.
• Knome provides full genome (98% genome) sequencing services for $4,998 for whole genome sequencing and interpretation for consumers, or $29,500 for whole genome sequencing and analysis for researchers, depending on requirements.
• meragenome.com Organisation working towards personal Genomics and Participatory Research in India
• Mapmygenome.in personal genomics company focused on the Indian genome
• HelloGene and HelloGenome personal genome information services describe genotyping and full genome sequencing launched by Theragen in Korea. HelloGenome is the first commercial whole genome sequencing service in Asia while HelloGene is the first in Korea. HelloGene uses Affymetrix SNP chips while HelloGenome uses Solexa machines.
• Illumina, Oxford Nanopore Technologies, Sequenom, Pacific Biosciences, Complete Genomics, and 454 Life Sciences are commercializing full genome sequencing but do not provide genetic analysis or counselling.