Perirhinal Cortex - Connectivity

Connectivity

The monkey perirhinal cortex receives a majority of its input from high-level visual areas, whereas, in the rat, its inputs are primarily olfactory and, to a lesser extent, auditory. Outputs to orbitofrontal cortex and medial prefrontal cortex regions (such as prelimbic and infralimbic) have been described. Perirhinal cortex also sends output to a number of subcortical structures, including the basal ganglia, the thalamus, the basal forebrain, and the amygdala.

It also has direct connections with hippocampus region CA1 and the subiculum. Perirhinal cortex projects to distal CA1 pyramidal cells, overlapping the projections from entorhinal cortex. The same CA1 cells send return projections back to perirhinal cortex. Inputs from subiculum terminate in both superficial and deep layers.