Voice Actors
- Kathleen Wilhoite: Pepper Ann Pearson, the protagonist of the series
- Clea Lewis: Nicky Little, Pepper Ann's best friend
- Danny Cooksey: Milo Kamalani, the other best friend of Pepper Ann's
- April Winchell: Lydia Pearson / Grandma Lilly / Ms. Stark
- Pamela Segall: Margaret Rose "Moose" Pearson, Pepper Ann's young sister
- Don Adams: Principal Hickey
- Paddi Edwards: Vera
- Susan Tolsky: Aunt Jainie Lilly Diggety
- Tino Insana: Uncle Jo Jo Diggety
- Jeff Bennett: Dieter Lederhosen /Pink-Eyed Pete / Shelf McClean / Craig Bean
- Jenna von Oy: Trinket St. Blair
- Kath Soucie: Cissy Rooney / Mrs. Little
- Cree Summer: Tessa & Vanessa James
- Tara Charendoff-Strong: Brenda
- Cam Clarke: Stewart Waldinger
- Kimmy Robertson: Gwen Mezzrow
- Candi Milo: Constance Goldman
- Adam Wylie: Crash
- Karen Duffy: Sketch
- Jim Cummings: Mr. Carter
- Don Lake: Mr. Finky
- Kathy Najimy: Coach Doogan
- James Avery: Mr. Clapper
- Maurice LaMarche: Chuck Pearson
- Brittany Murphy: Tank the 8th grader
Read more about this topic: Pepper Ann
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