Adverse Reactions
The occurrence of adverse drug reactions (ADRs) with PDE5 inhibitors appears to be dose related. Headache is a very common ADR, occurring in >10% of patients. Other common ADRs include: dizziness, flushing, dyspepsia, nasal congestion or rhinitis.
On October 18, 2007, the U.S. Food and Drug Administration (FDA) announced that a warning about possible sudden hearing loss would be added to drug labels of PDE5 inhibitors.
Since 2007 there is evidence that 5-phosphodiesterase inhibitors can cause an anterior optic neuropathy
Other ADRs and their incidence vary with the agent and are listed in their individual pages.
Read more about this topic: PDE5 Inhibitor
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