Afferent Inputs To The PVN
The PVN receives afferent inputs from many brain regions.
Among these, inputs from neurons in structures adjacent to the anterior wall of the third ventricle (the "AV3V region") carry information about the electrolyte composition of the blood, and about circulating concentrations of such hormones as angiotensin and relaxin, to regulate the magnocellular neurons.
Inputs from the brainstem (the nucleus of the solitary tract) and the ventrolateral medulla carry information from the heart and stomach. Inputs from the hippocampus to the CRH neurones are important regulators of stress responses.
Inputs from neuropeptide Y-containing neurons in the arcuate nucleus co-ordinate metabolic regulation (via TRH secretion) with regulation of energy intake.
Inputs from suprachiasmatic nucleus about levels of lighting (circadian rhythms).
Inputs from glucose sensors within the brain stimulate release of vasopressin and Corticotropin-releasing hormone from Parvocellular neurosecretory cells .
Read more about this topic: Paraventricular Nucleus Of Hypothalamus