Papago may refer to:
- An archaic term for Tohono O'odham people
- Papago (moth), a genus of geometer moths
- Papago Freeway, I-10 through Phoenix, Arizona
- Papago Freeway Tunnel, a tunnel in Arizona
- Papago Park, a park in Arizona
- Papago, a village in the northern part of the island of Saipan
- Papago, a GPS navigation product brand
- Papago Brewing, A Craft Beer Bar and Restaurant in Scottsdale