Colombia
From Yaviza, Panama southeast lies the virtually impenetrable Darién Gap, a 57-mile (92 km) stretch of some of the world's most rugged, mountainous jungle terrain. It is advised that travelers do not enter the Darién Gap as it is considered dangerous; it is a haven for bandits, smugglers, and Colombian paramilitary forces. The Colombian town nearest to the Darién Gap is Turbo, located in Antioquia province. The highway linking Turbo to Medellín is Colombia Route 62 and is approximately 278 km in length.
Travelers along the Inter-American Highway portion of the Pan-American Highway in Panama can take a ferry from Panama City to the port of Buenaventura, which is 115 km northwest of Cali. Cali represents a major junction between Buenaventura and two northern spurs of the Pan-American Highway that connect from northern Colombia and Venezuela.
Read more about this topic: Pan-American Highway (South America)