Opioid and Dopamine Systems in Pain and Pleasure
The neural systems to be explored when trying to for a neurochemical relationship between pain and pleasure are the opioid and dopamine systems. The opioid system is responsible for the actual experience of the sensation, whereas the dopamine system is responsible for the anticipation or expectation of the experience. Opioids work in the modulation of pleasure or pain relief by either blocking neurotransmitter release or by hyperpolarizing neurons by opening up a potassium channel which effectively temporarily blocks the neuron.
Read more about this topic: Pain And Pleasure
Famous quotes containing the words pain and pleasure, systems, pain and/or pleasure:
“When Socrates, after being relieved of his irons, felt the relish of the itching that their weight had caused in his legs, he rejoiced to consider the close alliance between pain and pleasure.”
—Michel de Montaigne (1533–1592)
“The skylines lit up at dead of night, the air- conditioning systems cooling empty hotels in the desert and artificial light in the middle of the day all have something both demented and admirable about them. The mindless luxury of a rich civilization, and yet of a civilization perhaps as scared to see the lights go out as was the hunter in his primitive night.”
—Jean Baudrillard (b. 1929)
“For pain is perhaps but a violent pleasure? Who could determine the point where pleasure becomes pain, where pain is still a pleasure? Is not the utmost brightness of the ideal world soothing to us, while the lightest shadows of the physical world annoy?”
—Honoré De Balzac (1799–1850)
“It has been from Age to Age an Affectation to love the Pleasure of Solitude, among those who cannot possibly be supposed qualified for passing Life in that Manner.”
—Richard Steele (1672–1729)