Opioid and Dopamine Systems in Pain and Pleasure
The neural systems to be explored when trying to for a neurochemical relationship between pain and pleasure are the opioid and dopamine systems. The opioid system is responsible for the actual experience of the sensation, whereas the dopamine system is responsible for the anticipation or expectation of the experience. Opioids work in the modulation of pleasure or pain relief by either blocking neurotransmitter release or by hyperpolarizing neurons by opening up a potassium channel which effectively temporarily blocks the neuron.
Read more about this topic: Pain And Pleasure
Famous quotes containing the words systems, pain and/or pleasure:
“In all systems of theology the devil figures as a male person.... Yes, it is women who keep the church going.”
—Don Marquis (1878–1937)
“I look on it as no trifling effort of female strength to withstand the artful and ardent solicitations of a man that is thoroughly master of our hearts. Should we in the conflict come off victorious, it hardly pays us for the pain we suffer from the experiment ... and I still persist in it that such a behaviour in any man I love would rob me of that most pleasing thought, namely, the obligation I have to him for not making such a trial.”
—Sarah Fielding (1710–1768)
“I became a virtuoso of deceit. It wasn’t pleasure I was after, it was knowledge. I consulted the strictest moralists to learn how to appear, philosophers to find out what to think and novelists to see what I could get away with. And, in the end, I distilled everything down to one wonderfully simple principle: win or die.”
—Christopher Hampton (b. 1946)