Padmini in Sanskrit means "She who sits on the lotus" and may refer to:
- Rani Padmini of Chittor (died 1303)
- Padmini (actress) (1932–2006), Indian actress and trained Bharathanatyam dancer who acted in over 250 Indian movies
- Kutty Padmini (born 1956), former child actor who acts mainly in Tamil cinema
- Padmini Kolhapure a Hindi actress during the 1980s (born 1965)
- Padmini Chettur (born 1970), contemporary Indian dancer trained by Chandralekha
- T. K. Padmini (1940–1969), painter from Kerala
- Premier Padmini was an automobile manufactured in India
- Padmini Rout (born 1994), chess prodigy from Orissa, India