Physiological Roles
P2X receptors are involved in a variety of physiological processes, including:
- Modulation of cardiac rhythm and contractility
- Modulation of vascular tone
- Mediation of nociception, especially chronic pain
- Contraction of the vas deferens during ejaculation
- Platelet aggregation
- Macrophage activation
- Apoptosis
- Neuronal-glial integration
Read more about this topic: P2X Purinoreceptor
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—Ellen Lewis (20th century)