Oxoguanine Glycosylase
| Gene Ontology | |
|---|---|
| Molecular function | • damaged DNA binding • endonuclease activity • protein binding • microtubule binding • oxidized purine nucleobase lesion DNA N-glycosylase activity • 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity |
| Cellular component | • nucleus • nucleoplasm • nucleolus • mitochondrion • nuclear matrix • nuclear speck |
| Biological process | • acute inflammatory response • DNA repair • base-excision repair • base-excision repair, AP site formation • nucleotide-excision repair • regulation of transcription, DNA-dependent • response to oxidative stress • response to radiation • response to estradiol stimulus • regulation of protein import into nucleus, translocation • response to drug • depurination • response to ethanol • response to folic acid • cellular response to cadmium ion |
| Sources: Amigo / QuickGO | |
9.79 – 9.83 Mb
113.33 – 113.34 Mb
| 8-oxoguanine DNA glycosylase, N-terminal domain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
structure of catalytically inactive q315a human 8-oxoguanine glycosylase complexed to 8-oxoguanine dna |
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| Identifiers | |||||||||
| Symbol | OGG_N | ||||||||
| Pfam | PF07934 | ||||||||
| Pfam clan | CL0407 | ||||||||
| InterPro | IPR012904 | ||||||||
| SCOP | 1ebm | ||||||||
| SUPERFAMILY | 1ebm | ||||||||
8-Oxoguanine glycosylase also known as OGG1 is a DNA glycosylase enzyme that, in humans, is encoded by the OGG1 gene. It is involved in base excision repair. It is found in bacterial, archaeal and eukaryotic species. Read more about Oxoguanine Glycosylase: Function, Interactions | |||||||||