Final Maturation and Release
Ovulation induction can also refer to the induction of the final maturation of already relatively developed ovarian follicles and their oocytes, as well as triggering oocyte release from the ovary. Colloquially, this is known as the "trigger shot." This induction of final maturation and release of oocytes is the physiological role the LH surge by luteinizing hormone.
Administration of medication for triggering of oocyte release avails for sexual intercourse or intrauterine insemination to be scheduled at ovulation, the most likely time to achieve pregnancy. In in vitro fertilization, induction of final maturation avails for egg retrieval when the eggs are fully mature.
Medications used for final maturation and/or release of oocytes include:
- A low dose of human chorionic gonadotropin (HCG or hCG), which may be injected after completed ovarian stimulation. Ovulation will occur between 38 and 40 hours after a single HCG injection. It is also used in in vitro fertilization, where it makes the follicles perform their final maturation. A transvaginal oocyte retrieval is then performed at a time usually between 34 and 36 hours after hCG injection, that is, just prior to when the follicles would rupture. HCG injection confers a risk of ovarian hyperstimulation syndrome.
- Induction of final maturation and/or release with a GnRH agonist is a valid alternative to HCG, resulting in an elimination of the risk of ovarian hyperstimulation syndrome. In in vitro fertilization, the delivery rate is approximately 6% less than with hCG triggering.
Read more about this topic: Ovulation Induction
Famous quotes containing the words final and/or release:
“Every gun that is made, every warship launched, every rocket fired, signifies, in the final sense, a theft from those who hunger and are not fed, those who are cold and are not clothed. The world in arms is not spending money alone. It is spending the sweat of its labourers, the genius of its scientists, the hopes of its children.”
—Dwight D. Eisenhower (1890–1969)
“The steel decks rock with the lightning shock, and shake with the
great recoil,
And the sea grows red with the blood of the dead and reaches for his spoil—
But not till the foe has gone below or turns his prow and runs,
Shall the voice of peace bring sweet release to the men behind the
guns!”
—John Jerome Rooney (1866–1934)