Ovarian Disease

Ovarian diseases can be classified as endocrine disorders or as a disorders of the reproductive system.

If the egg fails to release from the follicle in the ovary an ovarian cyst may form. Small ovarian cysts are common in healthy women. Some women have more follicles than usual (polycystic ovary syndrome), which inhibits the follicles to grow normally and this will cause cycle irregularities.

Other conditions include:

Ovarian cancer
Luteoma
Hypogonadism
Hyperthecosis

Endocrine pathology: endocrine diseases (E00–E35, 240–259)

Pancreas/
glucose
metabolism

Hypofunction

Diabetes mellitus

types:
- type 1
- type 2
- MODY 1 2 3 4 5 6
complications
- coma
- angiopathy
- ketoacidosis
- nephropathy
- neuropathy
- retinopathy
- cardiomyopathy

insulin receptor (Rabson–Mendenhall syndrome)
Insulin resistance

Hyperfunction

Hypoglycemia
beta cell (Hyperinsulinism)
G cell (Zollinger–Ellison syndrome)

Hypothalamic/
pituitary axes

Hypothalamus

gonadotropin
- Kallmann syndrome
- Adiposogenital dystrophy
CRH (Tertiary adrenal insufficiency)
vasopressin (Neurogenic diabetes insipidus)
general (Hypothalamic hamartoma)

Pituitary

Hyperpituitarism	anterior Acromegaly Hyperprolactinaemia Pituitary ACTH hypersecretion posterior (SIADH) general (Nelson's syndrome)

Hypopituitarism	anterior Kallmann syndrome Growth hormone deficiency ACTH deficiency/Secondary adrenal insufficiency GnRH insensitivity FSH insensitivity LH/hCG insensitivity posterior (Neurogenic diabetes insipidus) general Empty sella syndrome Pituitary apoplexy Sheehan's syndrome Lymphocytic hypophysitis

Thyroid

Hypothyroidism	Iodine deficiency Cretinism Congenital hypothyroidism Myxedema Euthyroid sick syndrome

Hyperthyroidism	Hyperthyroxinemia Thyroid hormone resistance Familial dysalbuminemic hyperthyroxinemia Hashitoxicosis Thyrotoxicosis factitia Graves' disease

Thyroiditis	Acute infectious Subacute De Quervain's Subacute lymphocytic Autoimmune/chronic Hashimoto's Postpartum Riedel's

Goitre	Endemic goitre Toxic nodular goitre Toxic multinodular goiter Thyroid nodule

Parathyroid

Hypoparathyroidism	Hypoparathyroidism Pseudohypoparathyroidism Pseudopseudohypoparathyroidism

Hyperparathyroidism	Primary Secondary Tertiary Osteitis fibrosa cystica

Adrenal

Hyperfunction

aldosterone: Hyperaldosteronism/Primary aldosteronism
- Conn syndrome
- Bartter syndrome
- Glucocorticoid remediable aldosteronism
AME
Liddle's syndrome
17α CAH

cortisol: Cushing's syndrome (Pseudo-Cushing's syndrome)

sex hormones: 21α CAH
11β CAH

Hypofunction/
Adrenal insufficiency
(Addison's, WF)

aldosterone: Hypoaldosteronism
- 21α CAH
- 11β CAH

cortisol: CAH
- Lipoid
- 3β
- 11β
- 17α
- 21α

sex hormones: 17α CAH

Gonads

ovarian: Polycystic ovary syndrome
Premature ovarian failure

testicular: enzymatic
- 5α-reductase deficiency
- 17β-hydroxysteroid dehydrogenase deficiency
- aromatase excess syndrome)
Androgen receptor (Androgen insensitivity syndrome

general: Hypogonadism (Delayed puberty)
Hypergonadism
- Precocious puberty
Hypoandrogenism
Hypoestrogenism
Hyperandrogenism
Hyperestrogenism

Height

Dwarfism/Short stature
- Laron syndrome
- Psychosocial
Gigantism

Multiple

Autoimmune polyendocrine syndrome multiple
- APS1
- APS2
Carcinoid syndrome
Multiple endocrine neoplasia
- 1
- 2A
- 2B
Progeria
- Werner syndrome
- Acrogeria
- Metageria
Woodhouse-Sakati syndrome

M: END

anat/phys/devp/horm

noco (d)/cong/tumr, sysi/epon

proc, drug (A10/H1/H2/H3/H5)

Female diseases of the pelvis and genitals (N70–N99, 614–629)

Internal

Adnexa

Ovary	Oophoritis · Ovarian cyst (Follicular cyst of ovary, Corpus luteum cyst, Theca lutein cyst) · Endometriosis of ovary · Ovarian hyperstimulation syndrome · Ovarian torsion · Ovarian apoplexy · Mittelschmerz · Female infertility (Anovulation, Poor ovarian reserve)

Fallopian tube	Salpingitis · Hydrosalpinx · Hematosalpinx · Female infertility (Fallopian tube obstruction)

Uterus

Endometrium	Endometritis · Endometriosis · Endometrial polyp · Endometrial hyperplasia · Asherman's syndrome · Dysfunctional uterine bleeding menstruation: flow (Amenorrhoea, Hypomenorrhea, Oligomenorrhea) · timing (Menorrhagia, Menometrorrhagia, Metrorrhagia) · pain (Dysmenorrhea, PMS) Female infertility (Habitual abortion)

Myometrium	Adenomyosis

Parametrium	Parametritis

Cervix	Cervicitis · Cervical polyp · Nabothian cyst · Cervical incompetence · Female infertility (Cervical stenosis) · Cervical dysplasia

General	Hematometra/Pyometra · Retroverted uterus

Vagina

Vaginitis (Bacterial vaginosis, Atrophic vaginitis, Candidal vulvovaginitis) · Leukorrhea/Vaginal discharge · Hematocolpos/Hydrocolpos Sexual dysfunction (Dyspareunia, Hypoactive sexual desire disorder, Sexual arousal disorder, Vaginismus) Prolapse (Cystocele, Rectocele, Enterocele, Sigmoidocele, Urethrocele) · Fistulae (Vesicovaginal, Rectovaginal) Vaginal bleeding

Other/general

Pelvic inflammatory disease · Pelvic congestion syndrome

External

Vulva	Vulvitis · Bartholin's cyst · Kraurosis vulvae · Vulvodynia

Clitoral hood or Clitoris	Clitoral phimosis · Clitorism

M: ♀ FRS

anat/phys/devp

noco/cong/npls, sysi/epon

proc/asst, drug (G1/G2B/G3CD)

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