Mitochondrial proteins
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Outer membrane |
fatty acid degradation (Carnitine palmitoyltransferase I, Long fatty acyl CoA synthetase)
tryptophan metabolism (Kynureninase)
monoamine neurotransmitter metabolism (Monoamine oxidase)
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Intermembrane space |
Adenylate kinase - Creatine kinase
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Inner membrane |
oxidative phosphorylation (Coenzyme Q - cytochrome c reductase, Cytochrome c, NADH dehydrogenase, Succinate dehydrogenase)
pyrimidine metabolism (Dihydroorotate dehydrogenase)
mitochondrial shuttle (Malate-aspartate shuttle, Glycerol phosphate shuttle)
other (Glutamate aspartate transporter, Glycerol-3-phosphate dehydrogenase, ATP synthase, Carnitine palmitoyltransferase II, Uncoupling protein)
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Matrix |
citric acid cycle (Citrate synthase, Aconitase, Isocitrate dehydrogenase, Oxoglutarate dehydrogenase, Succinyl coenzyme A synthetase, Fumarase, Malate dehydrogenase)
anaplerotic reactions (Aspartate transaminase, Glutamate dehydrogenase, Pyruvate dehydrogenase complex)
urea cycle (Carbamoyl phosphate synthetase I, Ornithine transcarbamylase, N-Acetylglutamate synthase)
alcohol metabolism (ALDH2)
PMPCB
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Other/to be sorted |
steroidogenesis (Cholesterol side-chain cleavage enzyme, Steroid 11-beta-hydroxylase, Aldosterone synthase), Frataxin
Mitochondrial membrane transport protein (Mitochondrial permeability transition pore, Mitochondrial carrier)
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Mitochondrial DNA |
Complex I (MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6) - Complex III (MT-CYB) - Complex IV (MT-CO1, MT-CO2, MT-CO3)
ATP synthase (MT-ATP6, MT-ATP8)
tRNA (MT-TA, MT-TC, MT-TD, MT-TE, MT-TF, MT-TG, MT-TH, MT-TI, MT-TK, MT-TL1, MT-TL2, MT-TM, MT-TN, MT-TP, MT-TQ, MT-TR, MT-TS1, MT-TS2, MT-TT, MT-TV, MT-TW, MT-TY)
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see also mitochondrial diseases
B strc: edmb (perx), skel (ctrs), epit, cili, mito, nucl (chro)
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