Otis Smith may refer to:
- Otis Smith (basketball), American basketball player
- Otis Smith (American football), American football player
- Otis M. Smith, justice on the Michigan Supreme Court
Famous quotes containing the words otis and/or smith:
“Miss Otis regrets she’s unable to lunch today.”
—Cole Porter (1893–1964)
“How awful to reflect that what people say of us is true!”
—Logan Pearsall Smith (1865–1946)