Osteoid Osteoma - Histological Findings

Histological Findings

On histological examination osteoid osteoma consists of a small (< 1.5–2 cm), yellowish to red nidus of osteoid and woven bone with interconnected trabeculae, and a background and rim of highly vascularized, fibrous connective tissue. Varying degrees of sclerotic bone reaction may surround the lesion. Benign osteoblastoma is virtually indistinguishable from osteoid osteoma. The usual appearance included a fibrovascular stroma with numerous osteoblasts, osteoid tissue, well-formed woven bone, and giant cells. The osteoblasts were generally small and regular in shape. "http://www.medscape.com/viewarticle/465365_2"

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