Explanation of Units
Since laboratories measure serum solutes in terms of freezing point depression, the reported units are properly units of osmolality. When a measure of serum solutes is calculated, it is often done in units of osmolarity. While it is possible to convert between osmolality and osmolarity, thereby deriving a more mathematically correct osmol gap calculation, in actual clinical practice this is not done. This is because the difference in absolute value of these two measurements that can be attributed to the difference in units will be negligible in a clinical setting. For this reason, the terms are often used interchangeably, though some object to equating the terms. Because the calculated osmol gap can therefore be a conflation of both terms (depending on how it is derived), neither term (osmolal gap nor osmolar gap) may be semantically correct. To avoid ambiguity, the terms "osmolal" and "osmolar" can be used when the units of molality or molarity are consistent throughout the calculation. When this is not the case, the term "osmol gap" can be used when units are mixed to provide a clinical estimate.
Read more about this topic: Osmol Gap
Famous quotes containing the words explanation of, explanation and/or units:
“There is a great deal of unmapped country within us which would have to be taken into account in an explanation of our gusts and storms.”
—George Eliot [Mary Ann (or Marian)
“My companion assumes to know my mood and habit of thought, and we go on from explanation to explanation, until all is said that words can, and we leave matters just as they were at first, because of that vicious assumption.”
—Ralph Waldo Emerson (1803–1882)
“Even in harmonious families there is this double life: the group life, which is the one we can observe in our neighbour’s household, and, underneath, another—secret and passionate and intense—which is the real life that stamps the faces and gives character to the voices of our friends. Always in his mind each member of these social units is escaping, running away, trying to break the net which circumstances and his own affections have woven about him.”
—Willa Cather (1873–1947)