Importance in Yeast Genetics
Mutations in the gene encoding OMP decarboxylase in yeast (URA3) leads to auxotrophy in uracil. in addition, a function OMP decarboxylase renders yeast strains sensitive to the molecule 5-fluoro orotic acid (5-FOA). The establishment of the URA3 gene as a selection marker with both positive and negative selection strategies has made the controlled expression of OMP decarboxylase a significant laboratory tool for the investigation of yeast genetics.
Read more about this topic: Orotidine 5'-phosphate Decarboxylase
Famous quotes containing the words importance and/or yeast:
“The importance of a lost romantic vision should not be underestimated. In such a vision is power as well as joy. In it is meaning. Life is flat, barren, zestless, if one can find one’s lost vision nowhere.”
—Sarah Patton Boyle, U.S. civil rights activist and author. The Desegregated Heart, part 1, ch. 19 (1962)
“Do you not know that a little yeast leavens the whole batch of dough?”
—Bible: New Testament, 1 Corinthians 5:6.