Antimicrobial Therapy
For more details on this topic, see Scrub typhus.O. tsutsugamushi is sensitive in vitro to doxycycline, rifampicin and azithromycin. It is innately resistant to all β-lactam antibiotics (for example, penicillin) because it lacks a peptidoglycan cell wall. Aminoglycosides (for example, gentamicin) are also ineffective in human infection because the organism is intracellular, and aminoglycosides do not penetrate intracellularly.
Read more about this topic: Orientia Tsutsugamushi
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