Organ-limited Amyloidosis - Neurological Amyloid

Neurological Amyloid

  • Alzheimer's disease (Aβ 39-43)
  • Parkinson's disease (alpha-synuclein)
  • Huntington's disease (huntingtin protein)
  • Transmissible spongiform encephalopathies caused by prion protein (PrP) were sometimes classed as amyloidoses, as one of the four pathological features in diseased tissue is the presence of amyloid plaques. These diseases include;
    • Creutzfeldt-Jakob disease (PrP in cerebrum)
    • Kuru (diffuse PrP deposits in brain)
    • Fatal Familial Insomnia (PrP in thalamus)
    • Bovine spongiform encephalopathy (PrP in cerebrum of cows)

Read more about this topic:  Organ-limited Amyloidosis

Famous quotes containing the word neurological:

    Nature, we are starting to realize, is every bit as important as nurture. Genetic influences, brain chemistry, and neurological development contribute strongly to who we are as children and what we become as adults. For example, tendencies to excessive worrying or timidity, leadership qualities, risk taking, obedience to authority, all appear to have a constitutional aspect.
    Stanley Turecki (20th century)