Major Intersections
- Note: mileposts do not reflect actual mileage due to realignments.
| County | Location | Mile | Destinations | Notes |
|---|---|---|---|---|
| Jackson | Ashland | 0.00 | OR 99 – Ashland City Center | |
| 1.32 | I-5 – Medford, Yreka | Interchange | ||
| 6.46 | Old Siskiyou Highway (OR 273) | |||
| Klamath | Klamath Falls | 58.86 | OR 140 west – Lake of the Woods, Fish Lake, Medford | West end of OR 140 overlap |
| 59.05 | US 97 / OR 140 east to OR 39 – Klamath Falls, Bend, Weed, Merrill, Lakeview | Interchange |
Read more about this topic: Oregon Route 66
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