Ordóñez or Ordoñez is a Spanish family name that may refer to:
- Ordóñez (bullfighter family)
- Antonio Ordóñez (1932–1998)
- Carmen Ordóñez (1955–2004)
- Cayetano Ordóñez
- Francisco Rivera Ordóñez (born 1974)
- Angel Gil-Ordoñez, Spanish conductor
- Francisco Fernández Ordóñez (1930–1992), Spanish politician who became Minister for Foreign Affairs in the PSOE
- Isidro Ordóñez, Franciscan friar in New Mexico in the 1610s
- José Batlle y Ordóñez (1856–1929), former president of Uruguay
- Juvenal Ordoñez, Peruvian politician
- Magglio Ordóñez (born 1974), Venezuelan Major League Baseball right fielder for the Detroit Tigers
- Miguel Ángel Fernández Ordóñez, Spanish politician of the Socialist Worker's Party and governor of the Bank of Spain
- Rey Ordóñez (born 1971), Cuban former Major League Baseball shortstop
- Salvador Diaz Ordóñez, an officer in the Spanish Army who designed artillery pieces in the late 19th and early 20th Centuries.
- Sancho I Ordóñez (c.895–929), Asturian king of Galicia
It can also be the name of a city:
- Ordóñez, a settlement in the Unión Department of Argentina
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