Signs and Symptoms
Symptoms include:
- opsoclonus (rapid, involuntary, multivectorial (horizontal and vertical), unpredictable, conjugate fast eye movements without intersaccadic intervals)
- myoclonus (brief, involuntary twitching of a muscle or a group of muscles)
- cerebellar ataxia, both truncal and appendicular
- aphasia (a language disorder in which there is an impairment of speech and of comprehension of speech, caused by brain damage)
- mutism (a language disorder in which a person does not speak despite evidence of speech ability in the past, often part of a larger neurological or psychiatric disorder)
- lethargy
- irritability or malaise
- drooling
- strabismus (a condition in which the eyes are not properly aligned with each other)
- vomiting
- sleep disturbances
About half of all OMS cases occur in association with neuroblastoma (a cancer of the sympathetic nervous system usually occurring in infants and children).
Read more about this topic: Opsoclonus Myoclonus Syndrome
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