One Gene-one Enzyme Hypothesis - Possible Anticipation of Beadle and Tatum's Results

Possible Anticipation of Beadle and Tatum's Results

Historian Jan Sapp has studied the controversy in regard to German geneticist Franz Moewus who, as some leading geneticists of the 1940s and 50s argued, generated similar results before Beadle and Tatum's celebrated 1941 work. Working on the algae Chlamydomonas, Moewus published, in the 1930s, results that showed that different genes were responsible for different enzymatic reactions in the production of hormones that controlled the organism's reproduction. However, as Sapp skillfully details, those results were challenged by others who found the data 'too good to be true' statistically, and the results could not be replicated.

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