Olney's Lesions - Serotonergic Drugs

Serotonergic Drugs

Serotonergic psychedelics such as psilocybin and LSD activate 5-HT (serotonin) receptors. Studies have shown that the serotonin systems affected by such serotonergic drugs are linked to the NMDA/glutamate systems. Tests on rats indicate that 5-HT agonists like LSD and psilocybin prevent the neurotoxicity caused by NMDA receptor antagonists.

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