Ocoee may refer to:
- The Toccoa/Ocoee River in Georgia and Tennessee
- Ocoee Middle School in Tennessee
- Ocoee, Florida, a city
- Ocoee, the Cherokee term for the Passiflora incarnata (Purple passionflower)
- USS Ocoee (SP-1208), a United States Navy patrol vessel in commission from 1917 to 1918