O-succinylbenzoate-Co A Ligase

O-succinylbenzoate-Co A Ligase

In enzymology, an o-succinylbenzoate-CoA ligase (EC 6.2.1.26) is an enzyme that catalyzes the chemical reaction

ATP + o-succinylbenzoate + CoA AMP + diphosphate + o-succinylbenzoyl-CoA

The 3 substrates of this enzyme are ATP, o-succinylbenzoate, and CoA, whereas its 3 products are AMP, diphosphate, and o-succinylbenzoyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is 2-succinylbenzoate:CoA ligase (AMP-forming). Other names in common use include 2-succinylbenzoyl-coenzyme A synthetase, and 2-succinylbenzoate:CoA ligase (AMP-forming). This enzyme participates in ubiquinone biosynthesis.

Read more about O-succinylbenzoate-Co A Ligase:  Structural Studies