The nuclear lamina is a dense (~30 to 100 nm thick) fibrillar network inside the nucleus of a eukaryotic cell. It is composed of intermediate filaments and membrane associated proteins. Besides providing mechanical support, the nuclear lamina regulates important cellular events such as DNA replication and cell division. Additionally, it participates in chromatin organization and it anchors the nuclear pore complexes embedded in the nuclear envelope.
The nuclear lamina is associated with the inner face of the bilayer nuclear envelope whereas the outer face stays continuous with the endoplasmic reticulum.
Read more about Nuclear Lamina: Structure and Composition, Role and Interaction Aspects, Laminopathies
Famous quotes containing the word nuclear:
“American universities are organized on the principle of the nuclear rather than the extended family. Graduate students are grimly trained to be technicians rather than connoisseurs. The old German style of universal scholarship has gone.”
—Camille Paglia (b. 1947)