NRE, an acronym or initialism, may refer to:
- National radio examiners
- New relationship energy
- Non-recurring engineering
- Non-recurring expenditure
- National Rail Enquiries
- National Railway Equipment
- National Register of Electors in Canada
- Null Reference Exception
- Net radiative effect
- negative regulatory element
- Non Resident External
- Department of Natural Resources and Environment (see Government of Victoria, Australia)
- In fluid mechanics and heat transfer, NRe is a common notation for the Reynolds number.