Effects
As a nerve agent, Novichok belongs to organophosphate acetylcholinesterase inhibitors. These chemical compounds inhibit the enzyme acetylcholinesterase, preventing the normal breakdown of neurotransmitter acetylcholine. Acetylcholine concentrations then increase at neuromuscular junctions to cause involuntary contraction of all muscles. This then leads to respiratory and cardiac arrest and finally death. The use of a fast-acting peripheral anticholinergic drug such as Atropine could block the receptors where acetylcholine acts to prevent poisoning (as is the treatment for poisoning by other acetylcholinesterare inhibitors). This is however quite dangerous in itself.
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